Determination of Adropin and Preptin Levels in the blood serum of Cyprinion macrostomus (Heckel, 1843)
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https://doi.org/10.5281/zenodo.8332814Keywords:
Adropin, Preptin, Cyprinion macrostomus, ELISA, Metabolic hormoneAbstract
Adropin and preptin have an important role in a range of physiological functions, from regulation of food intake to reproduction, immune function, energy expenditure, and lipid and carbohydrate metabolism. In this study, adropin and preptin levels were determined in the serum of Cyprinion macrostomus. The results were then compared based on gender. At the same time, the levels of these hormones were compared depending on length and weight. Hormone levels were measured by ELISA (Enzyme Labeled-Immunosorbent Analysis) method. It was determined that there was no significant difference between fish of different sexes in terms of adropin level in C. macrostomus (p > 0.05), but there was a statistically significant difference in terms of preptin level (p < 0.05). No correlation was found between serum adropin level of C. macrostomus and length (r = 0.76, p = 0.06) and weight (r = 0.136, p = 0.916).
References
Akpınar, M. A. (1999). Besinsel yağ asitlerinin ve açlığın Cyprinion macrostomus HECKEL, 1843’un kas dokusu yağ asit bileşimine etkisi. Turkish Journal of Biology, 23, 309–317.
Al-Habbib, O. A. M., & Al-Habbib, W. M. S. (1979). Acclimation to temperature and death at high changing lethal temperatures in Cyprinion macrostomus (Heckel). Journal of Thermal Biology, 4(1), 75-77
Aydın, R., Şen, D., Çalta, M., & Canpolat, Ö. (2008). The amount of calcium in bony structures used for age determination in Cyprinion macrostomus (Heckel, 1843). Aquaculture Research, 39, 596-602.
Aydin, S., Kuloglu, T., Aydin, S., Eren, M. N., Yilmaz, M., Kalayci, M., & Kendir, Y. (2013). Expression of adropin in rat brain, cerebellum, kidneys, heart, liver, and pancreas in streptozotocin-induced diabetes. Molecular and cellular biochemistry, 380, 73-81.
Buchanan, C. M., Phillips, A. R., & Cooper, G. J. (2001). Preptin derived from proinsulin-like growth factor II (proIGF-II) is secreted from pancreatic islet beta-cells and enhances insulin secretion. Biochemical Journal, 360, 431–439.
Butler, A. A., Tam, C. S., Stanhope, K. L., Wolfe, B. M., Ali, M. R., O'Keeffe, M., & Havel, P. J. (2012). Low circulating adropin concentrations with obesity and aging correlate with risk factors for metabolic disease and increase after gastric bypass surgery in humans. The Journal of Clinical Endocrinology & Metabolism, 97(10), 3783-3791.
Caf, F., Algul, S., & Koyun, M. (2017). Investigation of the irisin, preptin and adropin levels in the blood serum of Alburnus tarichi. Cellular and Molecular Biology, 63(8), 95-99.
Cooper, G. J., Willis, A. C., & Clark, A. (1987). Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. Proceedings of the National Academy of Sciences of the United States of America, 84, 8628–8632.
Duman, S., & Şahan, A. (2014). Kangal (Sivas) balıklı çermik termal kaplıcası ile Topardıç Deresi'nde (Sivas) yaşayan benekli sezen Cyprinion macrostomus (Heckel, 1843)’de bazı hematolojik parametreler ve non-spesifik immün yanıtın belirlenmesi. Yunus Araştırma Bülteni, 4, 21-28.
Ganesh-Kumar, K., Zhang, J., Gao, S., Rossi, J., McGuinness, O. P., Halem, H. H., & Butler, A. A. (2012). Adropin deficiency is associated with increased adiposity and insulin resistance. Obesity, 20(7), 1394-1402.
Geldiay, R., & Balık, S. (2007). Türkiye Tatlı Su Balıkları, Ege Üniversitesi Su Ürünleri Fakültesi Yayın No: 46, Ege üniversitesi Basımevi Bornova / İzmir, 532 S.
Gümgüm, B., Ünlü, E., Tez, Z., & Gülsün, Z. (1994). Heavy metal pollution in water, sediment and fish from the Tigris river in Türkiye. Chemosphere, 29, 111-116.
Kumar, K. G., Trevaskis, J. L., & Lam, D. D. (2008). Identification of adropin as a secreted factor linking dietary macronu-trient intake with energy homeostasis and lipid metabolism. Cell Metabolism, 8, 468–481.
Lian, A., Wu, K., Liu, T., Jiang, N., & Jiang, Q. (2016). Adropin induction of lipoprotein lipase expression in tilapia hepatocytes. Journal of Molecular Endocrinology, 56(11), 11-22.
Lubos, M., Mrázková, L., Gwozdiaková, P., Pícha, J., Buděšínský, M., Jiráček, J., & Žáková, L. (2022). Functional stapled fragments of human preptin of minimised length. Organic & Biomolecular Chemistry, 20(12), 2446-2454.
Metin, K., & Akpınar M. A. (2000). Cyprinion macrostomus (Heckel, 1843)’un gonatlarında total lipid ve yağ asidi miktarının mevsimsel değişimi. Turkish Journal of Biology, 24, 627–634.
Örün, İ., Dörücü, M., & Yazlak, H. (2003). Hematological parameters of three cyprinid fish species from Karakaya Dam Lake, Türkiye. Online Journal of Biological Sciences, 3(3), 320-328.
Özer, Z., Akpınar, M. A., Akçay, M., Erdem, Ü., Güler, R., Yanıkoğlu, A., Ergenoğlu, B., Dere, Ş., & Savaşçı, Ş. (1987). Kangal balıklı kaplıcanın (Sivas) bazı kimyasal ve biyolojik özelliklerinin araştırılması. Cumhuriyet Üniversitesi Fen-Edebiyat Fakültesi Fen Bilimleri Dergisi, 5(1), 1-34.
Saygı, G., & Bardakçı, F. (1990). Sivas Balıklı Çermik balıklarında bulduğumuz nematod parazit Rhabdochona türü. Türkiye Parazitoloji Dergisi, 14(1), 95-105.
Sayılı, M., Akca, H,. Duman, T., & Esengun, K. (2007). Psoriasis treatment via doctor fishes as part of health tourism: a case study of Kangal Fish Spring, Türkiye. Tourism Management, 28(2), 625-629.
Özdemir, N. Ş., Koyun, M., Caf, F., & Kırıcı, M. (2023). Factors affecting nutritional quality in terms of the fatty acid composition of Cyprinion macrostomus. Grasas y Aceites, 74(2), e508-e508.
Topuz, M., Celik, A., Aslantas, T., Demir, A. K., & Aydin, S. (2013). Plasma adropin levels predict endothelial dysfunction like flow-mediated dilatation in patients with type 2 diabetes mellitus. Journal of Investigative Medicine, 61, 1161–1164.
Undar, L., Akıpınar, A., & Yanıkoğlu, A. (1990). Doktor balıkları hastalığı yaladığı yer. Hospital Doctor 10 No 19,
Yang, G., Li, L., & Chen, W. (2009). Circulating preptin levels in normal, impaired glucose tolerance, and type 2 diabetic subjects. Annals of Medicine, 41(1), 52-56.
Yıldırım, T. (2012). Keban Baraj Gölü Balık Faunasının Tespiti, Devam eden Araştırma, Elazığ Su Ürünleri Araştırma Enstitüsü Müdürlüğü, Proje No: TAGEM/HAYSÜD/2004/07/03/01.
Zhang, C., Zhang, Q., Huang, Z., & Jiang, Q. (2020). Adropin inhibited tilapia hepatic glucose output and triglyceride accumulation via AMPK activation. Journal of Endocrinology, 246(2), 109-122.
Zhang, C., Yan, Y., Zhang, Q., & Jiang, Q. (2021). Molecular cloning and characterization of the novel adropin from tilapia (Oreochromis niloticus): Involvement in the control of food intake. Neuropeptides, 88, 102165.
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